Best Practices to Reduce Cancer Disparities Among LGBTI Populations
October 5th 2017In April 2017, the American Society of Clinical Oncology released a position statement, Strategies for Reducing Cancer Health Disparities Among Sexual and Gender Minority Populations, with the goal of educating healthcare providers about challenges faced by LGBTI individuals with cancer.
Death Rates Dropping, But Racial Disparities Remain in Breast Cancer
October 4th 2017Improved treatment and early detection mean fewer women in the United States are dying from breast cancer, according to a study released by the American Cancer Society (ACS) that examined trends in the disease.
Abemaciclib Approved for HR+/HER2- Breast Cancer
September 28th 2017The FDA approved abemaciclib (Verzenio) for use in combination with fulvestrant in women with HR+/HER2- advanced breast cancer with disease progression following endocrine therapy. The CDK4/6 inhibitor has also been approved as a monotherapy for patients with HR+/HER2- breast cancer with metastatic disease who have previously received endocrine therapy and chemotherapy.
New Cabazitaxel Dosage Approved for mCRPC
September 18th 2017FDA approval was given to a new regimen of cabazitaxel (Jevtana) to treat men with metastatic castration-resistant prostate cancer who previously received a docetaxel-containing regimen. The approval is for 20 mg/m2 every 3 weeks in combination with prednisone. The agency approved a dose of 25 mg/m2 every 3 weeks in this patient population in 2010.
Trial Update Confirms PFS Benefit With Cabozantinib Over Sunitinib in Advanced RCC
September 15th 2017Patients with untreated advanced renal cell carcinoma (RCC) lived significantly longer without disease progression when they received the multikinase inhibitor cabozantinib (Cabometyx) as initial therapy versus sunitinib (Sutent), according to results of an independent review of the randomized CABOSUN trial reported at the 2017 ESMO Congress in Madrid.
Durvalumab Shows "Clear Improvement" in Lung Cancer Outcomes
September 14th 2017"This is a clear improvement in the outcome, with increased PFS—by about 11 months—consistent improvement in response rate, and decreases in the development of metastatic disease," said lead investigator Luis Paz-Ares, MD, chair, Medical Oncology Department, Hospital Universitario Doce de Octubre.
"Triggers Tool" Gets Patients Into Palliative Care Earlier
September 13th 2017A new tool is helping healthcare providers determine who will benefit from palliative care starting early in the course of their treatment for cancer, according to the authors of a pilot study whose results were presented Sept. 9, during the 2017 European Society for Medical Oncology (ESMO) Congress in Madrid, Spain.
Statins, High Cholesterol May Decrease Breast Cancer Risk
September 13th 2017Can a class of drugs commonly prescribed to help lower cholesterol levels protect against breast cancer? A study recently presented at the European Society of Cardiology conference in Barcelona, Spain, offers interesting results.
Heart Problems, Fracture Risk Greater With Extended Use of Aromatase Inhibitors
September 12th 2017The authors noted that although some studies have shown improvement in breast cancer outcomes from extending treatment with AIs beyond the initial 5 years after diagnosis, there is not much research on the toxicity profile of extended use.
Surveillance for Papillary Thyroid Cancer
September 5th 2017A group of researchers led by a physician from Memorial Sloan Kettering Cancer Center in New York City examined the natural history and growth kinetics of low-risk papillary thyroid cancer (PTC), defined as intrathyroidal tumors ≤1.5 cm in size.
CAR T-cell Therapy Introduced With $475,000 Price Tag
August 31st 2017Tisagenlecleucel (Kymriah), Novartis' newly approved CAR T-cell therapy, will be put on the market with a price of $475,000 for a single infusion, an amount that is within the range anticipated by oncologists and that Novartis characterized as well below a price level that could be justified on cost.
First CAR T-Cell Therapy Approved in Pediatric, Young Adult ALL
August 30th 2017The FDA issued a historic approval of the first Chimeric Antigen Receptor (CAR) T-Cell Therapy, authorizing the use of tisagenlecleucel (Kymriah) for the treatment of patients up to 25 years of age with B-cell precursor acute lymphoblastic leukemia (ALL) that is refractory or in second or later relapse.