Endocrine Therapy May Eliminate Need for Surgery or Chemotherapy for Some Breast Cancer Patients
March 15th 2018Endocrine therapy can reduce tumor size in patients with ER-positive breast cancer. It can even help some patients avoid chemotherapy or even surgery. Deciding how long to continue this therapy can be tricky though.
FDA Grants Pembrolizumab Priority Review for Treatment of Cervical Cancer
March 13th 2018The FDA has granted priority review to a supplemental biologics license application for Pembrolizumab (Keytruda) for the treatment of advanced cervical cancer with disease progression on or after chemotherapy.
Ribociclib Benefits Premenopausal Women with Advanced Breast Cancer
March 10th 2018Ribociclib (Kisqali) improves progression-free survival (PFS) in pre- or perimenopausal women with hormone receptor–positive, HER2-negative advanced or metastatic breast cancer. These results, shared at 2018 Miami Breast Cancer Conference, were sustained across patient subgroups.
Hodgkin Lymphoma Survivors May Be at Greater Risk for Breast Cancer
March 6th 2018Radiotherapy treatments for Hodgkin lymphoma may raise the risk of certain breast cancer subtypes, a study of data on women survivors from the Surveillance, Epidemiology, and End Results (SEER) registries revealed.
Liquid Biopsy Use in Metastatic TNBC Demonstrates Prognostic Potential
March 2nd 2018Predicting survival outcomes for patients with metastatic triple-negative breast cancer (mTNBC) is now possible using liquid biopsy, according to results from a retrospective study published in the Journal of Clinical Oncology.
Nurses Can Help in Multidisciplinary Management of HIV-Infected Cancer
February 28th 2018As part of a multidisciplinary team, nurses often reference guidelines to assist in treatment decisions for patients with cancer. Now, they also have guidance on how to treat individuals that comprise an underserved population of patients: those living with HIV and cancer.
Clonal Evolution in MSI-H Colorectal Cancer Suggests Repeated Molecular Testing May Be Necessary
February 28th 2018Genetic changes that occur during DNA cloning in people with microsatellite instability-high (MSI-H) colorectal cancer may affect the efficacy of targeted and immunologic therapies. Repeated testing may be necessary to ensure that targeted treatments keep up with the changes in DNA.
FDA Approves Abemaciclib for Frontline Treatment of HR+/HER2- Advanced Breast Cancer
February 27th 2018Based on data from the phase III MONARCH 3 trial, the FDA has approved abemaciclib (Verzenio) for use in combination with an aromatase inhibitor for the frontline treatment of postmenopausal women with hormone receptor (HR)-positive, HER2-negative advanced or metastatic breast cancer.
Childhood Cancer Survivors at Risk for Heart Disease and Stroke
February 26th 2018Survivors of childhood cancer could be up to 20 times more likely to develop ischemic heart disease or to have strokes than their siblings. To determine their level of risk, researchers used a prediction model that included factors like gender, type of chemotherapy, and radiotherapy exposure to the head, neck, or chest.
Survivorship Tool Generates Effective Care Plans
February 22nd 2018Researchers developed the Head and Neck Survivorship Tool: Assessments and Recommendations (HN-STAR) to crunch patient-reported data and generate survivorship care plans to help those patients self-manage their care. Their study found that these plans could improve post-treatment care.
Women Who Undergo Lymph Node Dissection Regain Arm Mobility Faster With Exercise
February 21st 2018Lymph node surgery may be necessary to stop the spread of cancer, but it may cause people to have a limited range of motion. In addition to educating people about possible adverse effects, a new study suggests that nurses should also be explaining the benefits of physical therapy.
Geography, Race, and Genetic Variation in Endometrial Cancer
February 21st 2018A study done at SUNY Downstate Hospital found that black women of Caribbean descent with type I or type II endometrial cancer expressed significant differences in genetic variations when compared with a nationwide population of patients with endometrial cancer.
NCCN, ASCO Guide Nurses in Managing Checkpoint Inhibitor Side Effects
February 20th 2018Recognizing and understanding how to manage side effects related to immunotherapy treatements is key for nurses. To educate healthcare teams on immunotherapy-related toxicities, The National Comprehensive Cancer Network and the American Society of Clinical Oncology issued new guidelines.