Olaparib Significantly Improves PFS in Advanced BRCA+ Ovarian Cancer
November 6th 2018The PARP inhibitor olaparib (Lynparza) significantly improved progression-free survival (PFS) as frontline maintenance therapy in women with BRCA-positive advanced ovarian cancer, according to findings reported at the 2018 European Society of Medical Oncology Congress.
Frontline Alectinib Improves Survival in Asian Patients With ALK+ NSCLC
November 6th 2018Frontline alectinib (Alecensa), a next-generation tyrosine kinase inhibitor, enabled Asian patients with untreated ALK-positive advanced non–small cell lung cancer (NSCLC) to live significantly longer without disease progression compared with those who were treated with crizotinib (Xalkori) as initial therapy.
FDA Approves Lorlatinib for ALK-positive Non-Small Cell Lung Cancer
November 3rd 2018The FDA has granted lorlatinib (Lorbrena) an accelerated approval for the treatment of patients with ALK-positive metastatic non–small cell lung cancer (NSCLC) who have progressed on 1 or more ALK tyrosine kinases inhibitors (TKIs).
Trifluridine/Tipiracil Improves Survival in Heavily Pretreated Gastric/GEJ Cancer
November 2nd 2018Trifluridine/tipiracil (FTD/TPI; Lonsurf) reduced the risk of death in patients with heavily pretreated gastric or gastroesophageal junction (GEJ) cancer by 31% compared with placebo, according to data from the phase III TAGS trial.
Preparing for the Financial and Economic Impact of Biosimilars
November 2nd 2018A panel of experts gathered at a preconference presentation at the Association of Community Cancer Centers 35th National Oncology Conference in Phoenix to exchange their thoughts on the practical and theoretical considerations of incorporating biosimilars into the healthcare ecosystem.
Utilizing a Multidisciplinary Approach in Multiple Myeloma Assessment and Treatment
November 1st 2018Treatment for multiple myeloma is quickly evolving. To bring physicians, nurses, and other members of the community oncology care team up to date, Abhinav B. Chandra, MD, MSc, FACP, conducted a presentation at the Association of Community Cancer Centers (ACCC) 35th National Oncology Conference in Phoenix, Arizona.
Nurses Can Help Motivate Patients to Develop Healthy Behaviors
October 31st 2018At the Association of Community Cancer Centers (ACCC) 35th National Oncology Conference, Jessica Clague DeHart, PhD, MPH, discussed how clinicians can communicate the importance of physical activity and good nutrition practices to patients.
FDA Approves Pembrolizumab Regimen for Frontline Use in Squamous NSCLC
October 31st 2018The FDA has approved pembrolizumab (Keytruda) for first-line use in combination with carboplatin and either paclitaxel or nab-paclitaxel (Abraxane) for the treatment of patients with metastatic squamous non–small cell lung cancer (NSCLC).
Standard of Care Reigns Superior for Low-Risk HPV+ Oropharyngeal Cancer
October 29th 2018Though many patients with HPV-positive oropharyngeal cancer have been treated with cetuximab (Erbitux), results from the international De-ESCALaTE HPV trial showed that chemoradiotherapy, the current standard of care, is still the most effective.
FDA Grants Priority Review to Ruxolitinib for Acute GVHD
October 27th 2018The Food and Drug Administration has granted a priority review to the supplemental new drug application for ruxolitinib (Jakafi) to treat patients with acute graft-versus-host-disease (GVHD) who have had an inadequate response to corticosteroids.
FDA Grants Priority Review to TAS-102 for Advanced, Metastatic Gastric Cancer
October 26th 2018The Food and Drug Administration (FDA) has granted a priority review to the oral chemotherapy TAS-102 (trifluridine/tipiracil; Lonsurf) for use in previously treated patients with advanced or metastatic gastric adenocarcinoma, including cancer of the gastroesophageal junction.
Expanding Financial Advocacy Under the Value-Based System
October 24th 2018To help patients and programs meet the challenges of affording cancer treatments, community cancer centers are expanding the role of financial advocates in their organizations. Financial advocates may be financial counselors, nurses, navigators, social workers; pharmacy technicians; practice managers, and others.
FDA Grants Priority Review to Ibrutinib Plus Obinutuzumab in Frontline CLL
October 17th 2018The FDA has granted a priority designation to a supplemental new drug application (sNDA) for ibrutinib (Imbruvica) for use in combination with obinutuzumab (Gazyva) for the frontline treatment of adult patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL).
FDA Approves Second PARP Inhibitor to Treat Breast Cancer
October 16th 2018The FDA has approved talazoparib (Talzenna) for patients with deleterious or suspected deleterious germline BRCA-mutated, HER2-negative locally advanced or metastatic breast cancer, according to Pfizer, the manufacturer of the PARP inhibitor.
FDA Grants Breakthrough Designation to LOXO-292 for Thyroid Cancer Subtype
October 15th 2018The FDA has granted a breakthrough therapy designation to LOXO-292 for the treatment of patients with advanced RET fusion–positive thyroid cancer who require systemic therapy, have progressed on prior treatment, and have no other acceptable alternative treatment options.
Barbells for Boobs Partners With CancerCare to Launch Breast Cancer Support Line
October 12th 2018In an effort to help individuals gain access to breast health services, Barbells for Boobs and CancerCare®, the leading national cancer support organization, have officially launched the NYC Support Line.
FDA Advisory Committee Recommends Approval of Rituximab Biosimilar to Treat NHL
October 10th 2018The FDA’s Oncologic Drugs Advisory Committee (ODAC) recommended approval of CT-P10, a biosimilar for the monoclonal antibody rituximab (Rituxin), for 3 non-Hodgkin lymphoma indications in a 16-0 vote.
Higher Nursing Education Translates to Better Care for Patients
October 9th 2018For clinical nurse specialist and Oncology Nursing Society (ONS) member Anne Kolenic, DNP, APRN, AOCNS, her decision to pursue a DNP degree meant taking critical research results and implementing them to improve care at her institution.