Genetic Variants Influence Treatment, Surveillance of Children with Medulloblastoma
July 13th 2018Based on the identification of 6 gene variations that make carriers susceptible to developing medulloblastoma and possibly other cancers, researchers have proposed subgroup-based counseling and screening recommendations.
Heated Chemo During Resection Shows No Benefit in Advanced CRC
July 13th 2018The addition of heated chemotherapy delivered to the abdomen during surgery delivered no survival benefit to patients with peritoneal carcinomatosis, according to phase III study results presented at the 2018 ASCO Annual Meeting.
FDA Grants Priority Review to Frontline Pembrolizumab Combo in Metastatic NSCLC
July 2nd 2018The FDA granted a priority review to the anti-PD-1 agent pembrolizumab (Keytruda) in combination with chemotherapy as a first-line treatment for metastatic squamous non-small cell lung cancer (NSCLC), regardless of PD-L1 expression.
FDA Grants Priority Review to Glasdegib for Acute Myeloid Leukemia
June 28th 2018The FDA granted a priority review to a new drug application for glasdegib, an investigational oral smoothened inhibitor, for the treatment of adult patients with previously untreated acute myeloid leukemia in combination with low-dose cytarabine, a type of chemotherapy.
FDA Approves Neulasta Biosimilar to Reduce Post-Chemo Febrile Neutropenia in Some Cancers
June 5th 2018The FDA approved pegfilgrastim-jmdb (Fulphila) as the first biosimilar to pegfilgrastim (Neulasta), a drug designed to reduce the risk of febrile neutropenia in patients treated with chemotherapy in certain types of cancer, according to a press release issued by the FDA.
BLU-667 Shows Clinical Benefit in Advanced, RET-Altered Solid Tumors
April 20th 2018BLU-667 appeared to be well-tolerated and had broad clinical benefit among patients with advanced, RET-altered solid tumors who progressed on prior therapies, according to study findings from a phase I clinical trial presented at the AACR Annual Meeting 2018.
Pivot Nurse Role Improves Satisfaction, Quality of Life in Patients with Lung Cancer
April 12th 2018The Pivot Nurse in Oncology (PNO) role appears to make a substantial difference in care for patients being treated for advanced lung cancer, according to a study presented at the European Lung Cancer Congress (ELCC) 2018.
Nurses Play Critical Role in New Dosing Regimen for Nivolumab
March 20th 2018While the new FDA approval of 4-week dosing adds more flexibility in scheduling, it reduces the number of times patients would be monitored in person for adverse effects (AEs), so nurses need to be alert to and educated about potential AEs.
Nurses Can Help in Multidisciplinary Management of HIV-Infected Cancer
February 28th 2018As part of a multidisciplinary team, nurses often reference guidelines to assist in treatment decisions for patients with cancer. Now, they also have guidance on how to treat individuals that comprise an underserved population of patients: those living with HIV and cancer.