Fertility Preservation Guidelines Urge for Early Discussions with Young Patients with Cancer
July 2nd 2018Nurses treating young patients with cancer should be aware of the American Society of Clinical Oncology's updated guidelines and recommendations on fertility preservation, which were released in April 2018.
FDA Grants Priority Review to Frontline Pembrolizumab Combo in Metastatic NSCLC
July 2nd 2018The FDA granted a priority review to the anti-PD-1 agent pembrolizumab (Keytruda) in combination with chemotherapy as a first-line treatment for metastatic squamous non-small cell lung cancer (NSCLC), regardless of PD-L1 expression.
FDA Grants Priority Review to Glasdegib for Acute Myeloid Leukemia
June 28th 2018The FDA granted a priority review to a new drug application for glasdegib, an investigational oral smoothened inhibitor, for the treatment of adult patients with previously untreated acute myeloid leukemia in combination with low-dose cytarabine, a type of chemotherapy.
FDA Approves Binimetinib/Encorafenib for BRAF+ Melanoma
June 27th 2018The FDA has approved the combination of the BRAF inhibitor encorafenib (Braftovi) and the MEK inhibitor binimetinib (Mektovi) for the treatment of patients with BRAF-mutant unresectable or metastatic melanoma, as detected by an FDA-approved test.
FDA Grants Ibrutinib Combo Priority Review for NHL Subtype
June 25th 2018The FDA has granted a priority review to a supplemental new drug application for ibrutinib (Imbruvica) for use in combination with rituximab (Rituxan) as a treatment option across all lines of therapy for patients with Waldenström macroglobulinemia, a type of non-Hodgkin lymphoma (NHL).
Exploring CAR T-Cell Therapy as a Bridge to HCT in ALL
June 16th 2018Researchers at the National Institutes of Health are exploring whether CAR T-cell therapy can enhance the effectiveness of treatment with hematopoietic cell transplant (HCT) among patients with relapsed/refractory acute lymphoblastic leukemia (ALL).
FDA Approves Pembrolizumab for Treatment of Relapsed/Refractory PMBCL
June 13th 2018The FDA has granted an accelerated approval to pembrolizumab (Keytruda) for the treatment of adult and pediatric patients with refractory primary mediastinal large B-cell lymphoma (PMBCL), or those who have relapsed after 2 or more prior lines of therapy.
FDA Approves Bevacizumab Regimen for Ovarian Cancer Treatment After Surgery
June 13th 2018The FDA has approved bevacizumab (Avastin) for use in combination with carboplatin and paclitaxel, followed by bevacizumab monotherapy, for the treatment of patients with advanced ovarian cancer following initial surgical resection.
Talking About the Cost of Cancer Care With Patients
June 13th 2018During a session at the 2018 ASCO Annual Meeting, June 1-5, in Chicago, Illinois, Nipp and fellow panelists Ellen Miller Sonet, MBA, JD, chief strategy and policy officer, CancerCare, and Gery P. Guy Jr, PhD, MPH, of the Centers for Disease Control and Prevention, discussed the financial burdens of cancer diagnosis and treatment, the barriers facing clinicians and patients in discussing these financial burdens, and solutions that can be implemented to alleviate the burden.
FDA Grants Venetoclax Combination Full Approval for CLL
June 8th 2018Based on results from the phase III MURANO trial, the FDA has granted a regular approval to venetoclax (Venclexta) in combination with rituximab for the treatment of patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL), with or without 17p deletion, following at least 1 prior therapy.
FDA Approves Neulasta Biosimilar to Reduce Post-Chemo Febrile Neutropenia in Some Cancers
June 5th 2018The FDA approved pegfilgrastim-jmdb (Fulphila) as the first biosimilar to pegfilgrastim (Neulasta), a drug designed to reduce the risk of febrile neutropenia in patients treated with chemotherapy in certain types of cancer, according to a press release issued by the FDA.
Endocrine Therapy Alone Shows Benefit for Some with Early Breast Cancer
June 4th 2018Game-changing data published in the New England Journal of Medicine and presented during the 2018 ASCO Annual Meeting indicated that many women with HR+, HER2–, axillary node–negative breast cancer would see no significant benefit to having chemotherapy in addition to endocrine therapy.