Monitoring CML Patients: Effective Symptom Management Strategies for APPs
April 24th 2025Panelists discuss how advanced practice providers (APPs) implement effective monitoring strategies for patients with chronic myeloid leukemia (CML), including regular check-ins after starting new medications such as nilotinib, encouraging patients to maintain symptom journals, and providing holistic care that addresses both physical symptoms and emotional well-being to help patients successfully navigate life with a chronic disease.
Reducing Treatment Burdens: The Role of APPs in Enhancing CML Patient Quality of Life
April 24th 2025Panelists discuss how advanced practice providers (APPs) serve as crucial touchpoints throughout the journey of patients with chronic myeloid leukemia (CML), offering more accessible communication, early identification of adverse effects, medication management support, and integration of comprehensive supportive care services that collectively reduce emotional and logistical stress while improving overall quality of life.
The Impact of Cardiotoxicity Risks in CML: Navigating Dietary Guidelines with TKIs
April 17th 2025Panelists discuss how cardiovascular toxicity remains a significant concern with certain tyrosine kinase inhibitors (TKIs) used in chronic myeloid leukemia (CML) treatment, particularly with the older nilotinib formulation that showed increased cardiotoxicity in long-term trials, though it remains unclear whether this was directly related to poor adherence to fasting guidelines or inherent to the medication's pharmacological properties.
Addressing the Unmet Need in CML Treatment for Patient Treatment Adherence
April 17th 2025Panelists discuss how eliminating the strict mealtime restrictions with the new nilotinib formulation addresses a significant unmet need in chronic myeloid leukemia (CML) treatment by reducing disruption to patients' daily lives, potentially improving medication adherence and overall quality of life for patients who otherwise face a normal life expectancy when their condition is properly controlled.
Understanding the Significance of Nilotinib's New Formulation
April 10th 2025Panelists discuss how the new FDA-approved formulation of nilotinib offers significant advantages over the original version by eliminating fasting requirements, potentially improving patient adherence while maintaining efficacy and reducing the risk of toxicity-related complications such as glucose metabolism issues, elevated cholesterol, and pancreatitis.
How Has the CML Treatment Landscape Evolved Over the Past 5 Years?
April 10th 2025Panelists discuss how chronic myeloid leukemia (CML) treatment has evolved over the past 5 years, highlighting advancements in tyrosine kinase inhibitor (TKI) therapy, improved adverse effect management, tailored treatment approaches through molecular monitoring, and increased emphasis on shared decision-making with patients.
Managing Early HER2+ mBC: Patient-Centered Approaches and Evolving Treatment Strategies
Experts discuss how, it is crucial to approach treatment strategies with both compassion and transparency. It is important to explain the complexity of the situation and maintain clear and accessible language when discussing treatment strategies with patients and their families.
Experts discuss how, there is a role for SRS in treating brain metastases such as if a patient were to have a large singular brain metastasis that is causing symptoms such as seizures of neurological decline, that SRS could be a warranted treatment.
Evolving Treatment Strategies in Early HER2+ Breast Cancer
Experts discuss how, nearly half of patients diagnoses with HER-2 positive metastatic brain cancer do develop brain metastasis. It is thought that larger molecule treatments such as the monoclonal antibodies likely do not cross an intact blood brain barrier which is often why patients develop brain metastases