Karolina Faysman, NP; Linda M. Perry, PA-C; and Erin Kopp, DNP, ACNP-BC, discuss how chronic graft-vs-host disease (cGVHD) presents with variable symptoms affecting skin, joints, eyes, lungs, and more, which differs from acute GVHD. Symptom tracking, lifestyle modifications, and proactive communication help manage flares and complications. Patients benefit from structured documentation, daily self-assessment, and clear reporting to providers. Management evolves over time, requiring adaptable strategies.

An overview of the mechanisms of action (MOA) and detailed descriptions of the treatments for chronic graft-versus-host disease from first-line and beyond

Panelists discuss how medical professionals assess chronic graft-vs-host disease (cGVHD) severity using clinical grading systems, organ involvement, and functional impact to tailor treatment plans for optimal patient outcomes.