Impact of Goals of Care on Resource Use at End of Life
September 13th 2018Researchers exam­ined whether there were differences in resource use at end of life between patients with advanced cancer who identified goals of care focused heavily upon survival versus those who identified goals of care heavily focused on quality of life.
Glutaminase Inhibitor That Starves Tumor Cells May Improve Survival in Metastatic RCC
September 11th 2018A novel glutaminase inhibitor, CB-839, may provide a survival benefit in combination with cabozantinib (Cabometyx) by cutting off the energy supply to tumor cells in patients with metastatic renal cell carcinoma (RCC).
Novel RET Inhibitor Tested in Patients With NSCLC, MTC
September 11th 2018The phase I open-label LIBRETTO-001 clinical trial is currently testing LOXO-292, an oral small molecule inhibitor of RET signaling, to improve outcomes in patients with RET fusion–positive non–small cell lung cancer (NSCLC), medullary thyroid cancer (MTC), and other tumors with increased RET activity.