FDA Grants Priority Review to Nivolumab/Ipilimumab for Subgroup of Patients With Colorectal Cancer
March 27th 2018The FDA has granted a priority review to the combination of nivolumab (Opdivo) and ipilimumab (Yervoy) for the treatment of adult patients with microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR) metastatic colorectal cancer (mCRC) following progression on a fluoropyrimidine, oxaliplatin, and irinotecan.
Older Adults with Cancer and Diabetes May Require More Patient Education to Prevent ED Visits
March 26th 2018Emergency department (ED) visits are more common among older adults with diabetes. Oncology nurses need to be alert to patients with cancer who also have diabetes, and make sure they have the information they need to prevent unnecessary ED visits.
FDA Approves Nilotinib for Pediatric Chronic Myeloid Leukemia
March 22nd 2018Nilotinib (Tasigna) was approved by the FDA for the first- and second-line treatment of pediatric patients aged 1 year and older with Philadelphia chromosome–positive chronic myeloid leukemia in the chronic phase (Ph+ CML-CP).
Nurses Play Critical Role in New Dosing Regimen for Nivolumab
March 20th 2018While the new FDA approval of 4-week dosing adds more flexibility in scheduling, it reduces the number of times patients would be monitored in person for adverse effects (AEs), so nurses need to be alert to and educated about potential AEs.
Endocrine Therapy May Eliminate Need for Surgery or Chemotherapy for Some Breast Cancer Patients
March 15th 2018Endocrine therapy can reduce tumor size in patients with ER-positive breast cancer. It can even help some patients avoid chemotherapy or even surgery. Deciding how long to continue this therapy can be tricky though.
FDA Grants Pembrolizumab Priority Review for Treatment of Cervical Cancer
March 13th 2018The FDA has granted priority review to a supplemental biologics license application for Pembrolizumab (Keytruda) for the treatment of advanced cervical cancer with disease progression on or after chemotherapy.
Ribociclib Benefits Premenopausal Women with Advanced Breast Cancer
March 10th 2018Ribociclib (Kisqali) improves progression-free survival (PFS) in pre- or perimenopausal women with hormone receptor–positive, HER2-negative advanced or metastatic breast cancer. These results, shared at 2018 Miami Breast Cancer Conference, were sustained across patient subgroups.
Hodgkin Lymphoma Survivors May Be at Greater Risk for Breast Cancer
March 6th 2018Radiotherapy treatments for Hodgkin lymphoma may raise the risk of certain breast cancer subtypes, a study of data on women survivors from the Surveillance, Epidemiology, and End Results (SEER) registries revealed.
Liquid Biopsy Use in Metastatic TNBC Demonstrates Prognostic Potential
March 2nd 2018Predicting survival outcomes for patients with metastatic triple-negative breast cancer (mTNBC) is now possible using liquid biopsy, according to results from a retrospective study published in the Journal of Clinical Oncology.
Nurses Can Help in Multidisciplinary Management of HIV-Infected Cancer
February 28th 2018As part of a multidisciplinary team, nurses often reference guidelines to assist in treatment decisions for patients with cancer. Now, they also have guidance on how to treat individuals that comprise an underserved population of patients: those living with HIV and cancer.