Exploring CAR T-Cell Therapy as a Bridge to HCT in ALL
June 16th 2018Researchers at the National Institutes of Health are exploring whether CAR T-cell therapy can enhance the effectiveness of treatment with hematopoietic cell transplant (HCT) among patients with relapsed/refractory acute lymphoblastic leukemia (ALL).
FDA Approves Pembrolizumab for Treatment of Relapsed/Refractory PMBCL
June 13th 2018The FDA has granted an accelerated approval to pembrolizumab (Keytruda) for the treatment of adult and pediatric patients with refractory primary mediastinal large B-cell lymphoma (PMBCL), or those who have relapsed after 2 or more prior lines of therapy.
FDA Approves Bevacizumab Regimen for Ovarian Cancer Treatment After Surgery
June 13th 2018The FDA has approved bevacizumab (Avastin) for use in combination with carboplatin and paclitaxel, followed by bevacizumab monotherapy, for the treatment of patients with advanced ovarian cancer following initial surgical resection.
Talking About the Cost of Cancer Care With Patients
June 13th 2018During a session at the 2018 ASCO Annual Meeting, June 1-5, in Chicago, Illinois, Nipp and fellow panelists Ellen Miller Sonet, MBA, JD, chief strategy and policy officer, CancerCare, and Gery P. Guy Jr, PhD, MPH, of the Centers for Disease Control and Prevention, discussed the financial burdens of cancer diagnosis and treatment, the barriers facing clinicians and patients in discussing these financial burdens, and solutions that can be implemented to alleviate the burden.
FDA Grants Venetoclax Combination Full Approval for CLL
June 8th 2018Based on results from the phase III MURANO trial, the FDA has granted a regular approval to venetoclax (Venclexta) in combination with rituximab for the treatment of patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL), with or without 17p deletion, following at least 1 prior therapy.
FDA Approves Neulasta Biosimilar to Reduce Post-Chemo Febrile Neutropenia in Some Cancers
June 5th 2018The FDA approved pegfilgrastim-jmdb (Fulphila) as the first biosimilar to pegfilgrastim (Neulasta), a drug designed to reduce the risk of febrile neutropenia in patients treated with chemotherapy in certain types of cancer, according to a press release issued by the FDA.
Endocrine Therapy Alone Shows Benefit for Some with Early Breast Cancer
June 4th 2018Game-changing data published in the New England Journal of Medicine and presented during the 2018 ASCO Annual Meeting indicated that many women with HR+, HER2–, axillary node–negative breast cancer would see no significant benefit to having chemotherapy in addition to endocrine therapy.
FDA Grants Priority Review to Eltrombopag for Frontline Use in Severe Aplastic Anemia
May 31st 2018The FDA has granted a priority review to the oral thrombopoietin-receptor agonist eltrombopag (Promacta) in combination with standard immunosuppressive therapy as a frontline treatment for severe aplastic anemia.
Healthcare Teams Need to Learn More About Biosimilars
May 30th 2018A general lack of understanding of biosimilar drug terminology among clinicians, constantly evolving regulatory guidance, and the processes of prescribing and dispensing biosimilars is concerning, says the American Society of Clinical Oncology.
Oncology Nursing News Hosts Tweet Chat on Oncology Nursing Society's Annual Conference
May 21st 2018Oncology Nursing News® will be hosting its first tweet chat on May 23, at 1 p.m. ET, to discuss findings presented at the Oncology Nursing Society's Annual Conference, held May 17-20 in Washington, DC.
Distance Caregivers Often Experience More Distress and Anxiety Than Patients
May 19th 2018“While there is substantial research documenting the psychosocial characteristics in cancer patients and local caregivers to date, none have focused solely on the comparison of patients with their distance caregivers,” the researchers stated in an abstract presented by AnnMarie Papik, B.S.