Axillary Lymph Node Dissection Can Be Avoided in Some Patients With Clear Sentinel Nodes
December 16th 2016A recent study suggests that if a patient with breast cancer shows no signs of cancer prior to adjuvant chemotherapy and no signs of cancer after a sentinel lymph node biopsy (SLNB), an axillary lymph node biopsy (ALNB) could be avoided.
Loperamide Plus Budesonide Lessons Diarrhea With Neratinib in HER2+ Breast Cancer
December 9th 2016According to findings from a phase II trial, prophylactic treatment with a combination of loperamide and budesonide reduced the rate of all-grade diarrhea associated with neratinib to 65%, compared with 95.4% observed in the ExteNET trial.
Everolimus/Fulvestrant Combo Improves Survival in HR+ Breast Cancer
December 8th 2016According to phase II trial findings, adding everolimus to fulvestrant significantly improved progression-free survival for postmenopausal patients with metastatic hormone receptor-positive, HER2-negative breast cancer who are resistant to aromatase inhibitor therapy.
Five Years On, Ibrutinib's Benefits Sustained in CLL/SLL
December 6th 2016Five-year follow-up on ibrutinib (Imbruvica) shows efficacy and safety for patients with chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), with 89% of both treatment-naïve (TN) and relapsed patients experiencing a complete or partial response to the therapy.