Liquid Biopsy Use in Metastatic TNBC Demonstrates Prognostic Potential
March 2nd 2018Predicting survival outcomes for patients with metastatic triple-negative breast cancer (mTNBC) is now possible using liquid biopsy, according to results from a retrospective study published in the Journal of Clinical Oncology.
Nurses Can Help in Multidisciplinary Management of HIV-Infected Cancer
February 28th 2018As part of a multidisciplinary team, nurses often reference guidelines to assist in treatment decisions for patients with cancer. Now, they also have guidance on how to treat individuals that comprise an underserved population of patients: those living with HIV and cancer.
Clonal Evolution in MSI-H Colorectal Cancer Suggests Repeated Molecular Testing May Be Necessary
February 28th 2018Genetic changes that occur during DNA cloning in people with microsatellite instability-high (MSI-H) colorectal cancer may affect the efficacy of targeted and immunologic therapies. Repeated testing may be necessary to ensure that targeted treatments keep up with the changes in DNA.
FDA Approves Abemaciclib for Frontline Treatment of HR+/HER2- Advanced Breast Cancer
February 27th 2018Based on data from the phase III MONARCH 3 trial, the FDA has approved abemaciclib (Verzenio) for use in combination with an aromatase inhibitor for the frontline treatment of postmenopausal women with hormone receptor (HR)-positive, HER2-negative advanced or metastatic breast cancer.
Childhood Cancer Survivors at Risk for Heart Disease and Stroke
February 26th 2018Survivors of childhood cancer could be up to 20 times more likely to develop ischemic heart disease or to have strokes than their siblings. To determine their level of risk, researchers used a prediction model that included factors like gender, type of chemotherapy, and radiotherapy exposure to the head, neck, or chest.
Survivorship Tool Generates Effective Care Plans
February 22nd 2018Researchers developed the Head and Neck Survivorship Tool: Assessments and Recommendations (HN-STAR) to crunch patient-reported data and generate survivorship care plans to help those patients self-manage their care. Their study found that these plans could improve post-treatment care.
Women Who Undergo Lymph Node Dissection Regain Arm Mobility Faster With Exercise
February 21st 2018Lymph node surgery may be necessary to stop the spread of cancer, but it may cause people to have a limited range of motion. In addition to educating people about possible adverse effects, a new study suggests that nurses should also be explaining the benefits of physical therapy.
Geography, Race, and Genetic Variation in Endometrial Cancer
February 21st 2018A study done at SUNY Downstate Hospital found that black women of Caribbean descent with type I or type II endometrial cancer expressed significant differences in genetic variations when compared with a nationwide population of patients with endometrial cancer.
NCCN, ASCO Guide Nurses in Managing Checkpoint Inhibitor Side Effects
February 20th 2018Recognizing and understanding how to manage side effects related to immunotherapy treatements is key for nurses. To educate healthcare teams on immunotherapy-related toxicities, The National Comprehensive Cancer Network and the American Society of Clinical Oncology issued new guidelines.
Younger Cancer Survivors Put Themselves at Risk When They Fail to Seek Follow-Up Care
February 19th 2018Many adolescent and young adult (AYA) survivors of cancer end up "lost to follow-up," according to recent research. Nurses charged with patient education should take heed, and be sure to stress the importance of follow-up care to their AYA patients and their families.
FDA Grants Priority Review to Ivosidenib for IDH1-Mutant AML
February 15th 2018Agios Pharmaceuticals announced that the FDA has granted a priority review designation to its targeted therapy, ivosidenib (AG-120), for the treatment of patients with relapsed/refractory IDH1-mutant acute myeloid leukemia (AML).
USPSTF Recommends Against Ovarian Cancer Screening in Average- to Low-Risk Women
February 15th 2018Screening for ovarian cancer in asymptomatic women who are not known to have a high-risk hereditary cancer syndrome has no benefit and may lead to harm due to false positives, according to a new review conducted by the US Preventive Services Task Force (USPSTF).
First Treatment for Nonmetastatic Castration-Resistant Prostate Cancer Approved by FDA
February 15th 2018Patients with nonmetastatic castration-resistant prostate cancer now have their first FDA-approved treatment. Apalutamide (Erleada) was approved based on the phase III SPARTAN trial in which apalutamide reduced the risk of metastasis or death by 72% in patients with nonmetastatic CRPC.
FDA Grants Priority Review to Lorlatinib for Patients With ALK+ NSCLC
February 13th 2018Pfizer announced that the FDA has granted a priority review to a new drug application for lorlatinib, an ALK inhibitor, for use in patients with ALK-positive metastatic non–small cell lung cancer (NSCLC) who have progressed on 1 or more ALK tyrosine kinase inhibitors.
Patient Navigation Initiative Takes Aim at Health Disparities
February 12th 2018Patient navigation is playing an increasingly vital role in guiding patients with breast cancer through the maze of the American healthcare system. The Patient Navigation Initiative is a pioneering project of Susan G. Komen of Greater New York City focused on helping women overcome barriers to care, which leads to improved outcomes.
Palliative Care Services Are on the Rise but More Progress Is Needed
February 12th 2018Eighty percent of hospitalized patients in the U.S. have access to palliative care services. But that means that 20% do not. For patients with cancer, this can potentially mean the difference between effective symptom management and end-of-life care, and inadequate usual care.
LivingWith App Helps Patients with Cancer Manage their Experience
February 12th 2018The LivingWith app helps patients connect with a close circle of contacts and enables them to ask for help with daily tasks, track their symptoms, and collect important documents and information from appointments.