Optimizing Treatment Strategies for Advanced Upper GI Cancers

Experts discuss key immune-related adverse events (irAEs) to monitor in patients receiving nivolumab, how to differentiate these from disease-related symptoms, and how to manage moderate to severe irAEs, including factors that determine whether immunotherapy should be paused or discontinued.

Experts discuss Robert’s journey with HER2-positive upper gastrointestinal (GI) cancer, highlighting key treatment approaches and challenges.

Experts discuss the most common adverse events associated with the FOLFOX regimen and effective strategies for early detection and management.

Experts discuss the role of supportive therapies, such as antiemetics, nutritional support, and physical activity, in improving outcomes and patient comfort during treatment.

Experts discuss effective communication strategies for managing patient and caregiver expectations about treatment adverse effects and their potential impact on daily life.

Experts discuss how to balance treatment intensity with maintaining quality of life, particularly in patients with advanced-stage disease.

Experts discuss Megan’s journey with HER2-positive upper gastrointestinal (GI) cancer, highlighting key treatment strategies and challenges.

Experts discuss the most common adverse events associated with trastuzumab deruxtecan, how to effectively identify and manage them to minimize treatment interruptions, and how to monitor and address interstitial lung disease (ILD), a known potential adverse effect of trastuzumab deruxtecan.

Experts discuss how to manage fatigue, abdominal pain, and other treatment-related symptoms to maintain or improve quality of life for patients undergoing HER2-targeted therapy and share strategies for supporting patients with declining performance status (eg, ECOG performance status [PS] 2) in balancing treatment efficacy with daily functioning.

Experts discuss how they collaborate with oncologists, nutritionists, and other specialists to manage complex cases involving advanced disease and treatment-related adverse effects (AEs) and the role of the multidisciplinary team in addressing specific patient needs, such as nutritional deficits, pain management, or psychosocial challenges.

Experts discuss how to facilitate open communication among the patient, caregivers, and the multidisciplinary team to ensure comprehensive care and alignment on treatment goals.